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Alendronate inhibition of protein-tyrosine-phosphatase-meg1

✍ Scribed by Evan E Opas; Su Jane Rutledge; Ellis Golub; Andrew Stern; Zoran Zimoio; Gideon A Rodan; Azriel Schmidt


Book ID
119407361
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
700 KB
Volume
54
Category
Article
ISSN
0006-2952

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PTP-MEG2 is an intracellular protein tyrosine phosphatase with a putative lipid-binding domain at the N-terminus. The present study reports expression, purification, and characterization of the full-length form of the enzyme plus a truncated form containing the catalytic domain alone. Full-length PT