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Tiludronate inhibits protein tyrosine phosphatase activity in osteoclasts

✍ Scribed by H. Murakami; N. Takahashi; S. Tanaka; I. Nakamura; N. Udagawa; S. Nakajo; K. Nakaya; M. Abe; Y. Yuda; F. Konno; A. Barbier; T. Suda

Book ID
119650746
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
737 KB
Volume
20
Category
Article
ISSN
8756-3282

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An osteoclastic protein-tyrosine phospha
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## Abstract This study tested the hypothesis that an osteoclastic protein‐tyrosine phosphatase, PTP‐oc, enhances osteoclast activity through c‐Src activation. The effects of several resorption activators and inhibitors on PTP‐oc expression, resorption activity, and c‐Src activation were determined