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Age at exposure and Apc status influence the levels of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adducts in mouse intestine and liver

✍ Scribed by Inger-Lise Steffensen; Herman A.J. Schut; Jan Alexander


Book ID
116759017
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
486 KB
Volume
587
Category
Article
ISSN
1383-5718

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## Abstract 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐__b__]pyridine (PhIP) is the most abundant heterocyclic amine derived from food, possibly involved in human carcinogenesis. We evaluated the formation of PhIP‐DNA adducts in lymphocytes from 76 incident colorectal cancer patients likely to be exposed