Affinity-based selection and the germinal center response
โ Scribed by Tyani D. Chan; Robert Brink
- Book ID
- 114796077
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 393 KB
- Volume
- 247
- Category
- Article
- ISSN
- 0105-2896
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The germinal center (GC) is an important anatomical site for the development of high affinity antibodies during T-cell dependent B cell responses. Although the importance of the GC response to humoral immunity is well known, much remains to be elucidated about GC induction, maintenance and regulatio
During germinal center reactions, the appearance of two specific zones are observed: the dark and the light zone. Up to now, the origin and function of these zones are poorly understood. In the framework of a stochastic and discrete model, several possible pathways of zone development during germina