Refolding of therapeutic proteins produc
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Satoru Misawa; Izumi Kumagai
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Article
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1999
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Wiley (John Wiley & Sons)
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English
β 190 KB
Overexpression of cloned or synthetic genes in Escherichia coli often results in the formation of insoluble protein inclusion bodies. Within the last decade, specific methods and strategies have been developed for preparing active recombinant proteins from these inclusion bodies. Usually, the inclus