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[Advances in Clinical Chemistry] Volume 57 || Somatic Mitochondrial DNA Mutations in Human Cancers

✍ Scribed by Yu, Man

Book ID
118271566
Publisher
Elsevier
Year
2012
Weight
410 KB
Category
Article
ISBN
0123943841

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## Abstract We sequenced the entire mitochondrial genome in 8 chromophobe renal cell carcinomas (RCCs) and corresponding normal kidneys. Our study disclosed 68 known and 45 new sequence variations occurring 132 and 45 times, respectively. We found 6 somatic nucleotide changes in 5 out of the 8 chro