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[Advances in Cancer Research] Volume 97 || Structural Biology of the Tumor Suppressor p53 and Cancer‐Associated Mutants

✍ Scribed by Joerger, Andreas C.


Book ID
120885771
Publisher
Elsevier
Year
2007
Weight
557 KB
Category
Article
ISBN
0120066971

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## Abstract Drug resistance remains a key obstacle to successful cancer treatment. The implementation of pharmacogenomics is widely proclaimed as a route to revolutionize the face of cancer therapy. Here we discuss the pharmacogenomics of the p53 tumor suppressor and its role in cancer chemosensiti