VRML in Cancer Research Local Molecular Properties of the p53 Tumor Suppressor Protein-DNA Interface
✍ Scribed by Gerd Moeckel; Matthias Keil; Bertold Spiegelhalder; Jürgen Brickmann
- Publisher
- Springer-Verlag
- Year
- 1996
- Tongue
- English
- Weight
- 105 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1610-2940
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## Abstract The p53 tumor suppressor gene, which is frequently mutated in a wide variety of tumors, plays an important role in maintaining genomic integrity. Following genotoxic insults, the protein level of p53 is increased, and p53 functions as a sequence‐specific transcription factor that regula