Diabetic foot disease is an important complication of diabetes. The development and outcome of foot ulcers are related to the interplay between numerous diabetes-related factors such as nerve dysfunction, impaired wound healing and microvascular and/or macrovascular disease. The formation of advanc
Advanced glycation end products downregulate glucokinase in mice
β Scribed by Hongsoo Jung; Jindeok Joo; Yeonsu Jeon; Junga Lee; Janghyeok In; Daewoo Kim; Eujin Kang; Yongshin Kim; Yonggul Lim; Jaehyeok Kang; Jinwoo Choi
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 120 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1520-7552
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## Abstract Advanced glycation endβproducts (AGE) play a role in the pathogenesis of several diseases, including diabetic complications and atherosclerosis. In atherosclerotic lesions of human aortas, AGE are localized in the extracellular matrix and intracellularly in foam cells. Two interpretatio
## Abstract ## Objectives/Hypothesis: Advanced glycation end products (AGE) have recently been implicated in aging changes within different tissues of the body. The role of AGEs and their receptors in the mammalian inner ear is largely unknown. In this study we analyzed for the expression of two A