The objective of this work is to develop bloodcontacting surfaces that will dissolve nascent clots that may begin to form on them. Surfaces were prepared consisting of a polyurethane to which a coating reagent was attached covalently by photochemical methods. The coating reagent was a polyacrylamide
Adsorption of plasminogen to glass and polyurethane surfaces
β Scribed by K.A Woodhouse; P.W Wojciechowski; J.P Santerre; J.L Brash
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 755 KB
- Volume
- 152
- Category
- Article
- ISSN
- 0021-9797
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Silica glass and silylated silica glass have been used extensively as model surfaces for studying the interactions of biological systems with specific chemical functions. In this work, the adsorption of plasminogen to silylated silica glass materials has been investigated with the objective of provi
The adsorption of fibrinogen and plasminogen from plasma to silica glass, sulfonated silica glass, and lysinederivatized silica glass has been investigated. The data indicate that the sulfonated material has a high affinity for both fibrinogen and plasminogen, but that the ratio of plasminogen to fi