Infrared internal reflection spectroscopy has been used to study the adsorption of certain plasma proteins on a variety of hydrophobic polymer surfaces. The behavior of the systems studied was almost identical. Under static conditions the proteins appear to be rapidly adsorbed as monomolecular layer
Adsorption of plasma proteins on hydrophobic surfaces. III. Serum, plasma, and blood
✍ Scribed by Bagnall, R. D.
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 532 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0021-9304
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✦ Synopsis
Abstract
Liquid–air and liquid–liquid interfaces were used as models for the liquid‐solid system of plasma proteins and hydrophobic surfaces in the study of adsorption of serum, plasma, and blood onto these surfaces. The interfacial tension is determined for three phases: air, methylene iodide, and isooctane. Curves of interfacial tension versus time for the various systems are given from which a triple‐intersection point, where the protein solution is in equilibrium with each surface, is found. It is shown that albumin, γ‐globulin, and a mixed solution of these at in vivo concentrations behave in characteristic and constant manners at the three interfaces of air, methylene iodide, and isooctane. A range of synthetic surfaces which have constant behavior at equilibrium is deduced and it is concluded that any soft tissue response differences between such surfaces could not be the result of albumin or γ‐globulin.
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