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Adrenergic Regulation of the HERG Potassium Channel Biosynthesis and Function

✍ Scribed by Krishnan, Yamini; Chen, Jian; McDonald, Thomas V.


Book ID
119206871
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
39 KB
Volume
98
Category
Article
ISSN
0006-3495

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The human ether‐à‐go‐go related gene (hERG) encodes a protein that forms a voltage‐gated potassium channel and plays an important role in the heart by controlling the rapid delayed rectifier K^+^ current (__I__~Kr~). The S4–S5 linker was shown to be important for the gating of the hERG channel. Nucl