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Role of intracellular domains in the function of the herg potassium channel

✍ Scribed by Moza Al-Owais; Kate Bracey; Dennis Wray


Publisher
Springer
Year
2009
Tongue
English
Weight
728 KB
Volume
38
Category
Article
ISSN
1432-1017

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The solution structure of the S4–S5 link
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The human ether‐à‐go‐go related gene (hERG) encodes a protein that forms a voltage‐gated potassium channel and plays an important role in the heart by controlling the rapid delayed rectifier K^+^ current (__I__~Kr~). The S4–S5 linker was shown to be important for the gating of the hERG channel. Nucl