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Adenosine triphosphate is full antagonist at human P2Y1 purinoceptors

✍ Scribed by Katrin Sak; Jaak Järv

Book ID
117470662
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
125 KB
Volume
284
Category
Article
ISSN
0304-3940

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✍ Noel J. Cusack; Caroline J. Pettey 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 910 KB

Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P,,-purinoceptors. Both of these effects of ADP are inhibited competitively by ATP. Structure-activity relationships for phosphate-modified analogs of ADP and adenosine 5'-tri