Adenosine receptor activation in quiescent Swiss 3T3 cells: Enhancement of cAMP levels, DNA synthesis and cell division
β Scribed by Enrique Rozengurt
- Book ID
- 115891587
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 647 KB
- Volume
- 139
- Category
- Article
- ISSN
- 0014-4827
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π SIMILAR VOLUMES
Micromolar concentrations of AI3+ are shown to be strongly mitogenic for quiescent cultures of Swiss 3T3 and 3T6 cells. AI3+ caused a striking shift in the dose-response curve for the effect of fetal bovine serum on 3H-thymidine incorporation. In the absence of serum the mitogenic effect of aluminum
## Abstract Purine nucleotides and nucleosides were found to enhance the DNA synthesis in quiescent 3T3 cells induced either by fresh medium containing calf serum or by the addition of the Ξ²βglobulin serum fraction to depleted medium. A two to threefold enhancement has been obtained under these con