𝔖 Bobbio Scriptorium
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Adenosine kinase inhibition protects brain against transient focal ischemia in rats

✍ Scribed by Ning Jiang; Elizabeth A Kowaluk; Chi-Hung Lee; Hormoz Mazdiyasni; Michael Chopp

Book ID
117099046
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
203 KB
Volume
320
Category
Article
ISSN
0014-2999

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## Abstract Heme oxygenase‐1 (HO1) catalyzes oxidation of the heme molecule in concert with NADPH‐cytochrome P450 reductase following the specific cleavage of heme into carbon monoxide, iron, and biliverdin, which is rapidly metabolized to bilirubin. HO1 is a stress‐inducible protein that protects