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Adenosine deaminase inhibitors: synthesis and structure activity relationships of imidazole analogs of erythro-9-(2-hydroxy-3-nonyl)adenine

โœ Scribed by Cristalli, Gloria; Eleuteri, Alessandra; Franchetti, Palmarisa; Grifantini, Mario; Vittori, Sauro; Lupidi, Giulio


Book ID
121366506
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
831 KB
Volume
34
Category
Article
ISSN
0022-2623

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๐Ÿ“œ SIMILAR VOLUMES


Adenosine deaminase inhibitors: Structur
โœ Gloria Cristalli; Alessandra Eleuteri; Sauro Vittori; Rosaria Volpini; Emidio Ca ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 475 KB

Adenosine deaminase (ADA) is the enzyme which catalyzes the irreversible deamination of adenosine and deoxyadenosine to inosine and deoxyinosine, respectively. It is widely distributed in vertebrate tissues and i s thought to be essential for proper functioning of mammalian cells. ADA inhibitors may