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Adenosine deaminase inhibitors. Conversion of a single chiral synthon into erythro- and threo-9-(2-hydroxy-3-nonyl)adenines

โœ Scribed by Bastian, Gerard; Bessodes, Michel; Panzica, Raymond P.; Abushanab, Elie; Chen, Shih Fong; Stoeckler, Johanna D.; Parks, Robert E.


Book ID
127303219
Publisher
American Chemical Society
Year
1981
Tongue
English
Weight
375 KB
Volume
24
Category
Article
ISSN
0022-2623

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Adenosine deaminase inhibitors: Structur
โœ Gloria Cristalli; Alessandra Eleuteri; Sauro Vittori; Rosaria Volpini; Emidio Ca ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 475 KB

Adenosine deaminase (ADA) is the enzyme which catalyzes the irreversible deamination of adenosine and deoxyadenosine to inosine and deoxyinosine, respectively. It is widely distributed in vertebrate tissues and i s thought to be essential for proper functioning of mammalian cells. ADA inhibitors may