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Additive effects of inducers and fasting on acetaminophen hepatotoxicity

✍ Scribed by Dominique Pessayre; Joao-Carlos Wandscheer; Barton Cobert; Regine Level; Claude Degott; Anne Marie Batt; Nicole Martin; Jean Pierre Benhamou

Book ID
115775073
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
520 KB
Volume
29
Category
Article
ISSN
0006-2952

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✍ Thomas B. Leonard; D. Gwyn Morgan; John G. Dent πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 970 KB

Cimetidine has been shown to protect against acetaminophen-mediated hepatotoxicity in both rats and mice. In contrast to cimetidine, ranitidine recently has been determined to potentiate the hepatotoxic action of acetaminophen in Fischer 344 rats. The present studies were designed to characterize th