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Therapeutic effect of cimetidine on acetaminophen-induced hepatotoxicity in rabbits

โœ Scribed by Javad Sajedianfard; Mahdi Saeb; Muhammad-Reza Edalatpisheh

Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
135 KB
Volume
18
Category
Article
ISSN
1618-5641

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Ranitidine-acetaminophen interaction: Effects on acetaminophen-induced hepatotoxicity in fischer 344 rats
โœ Thomas B. Leonard; D. Gwyn Morgan; John G. Dent ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 970 KB

Cimetidine has been shown to protect against acetaminophen-mediated hepatotoxicity in both rats and mice. In contrast to cimetidine, ranitidine recently has been determined to potentiate the hepatotoxic action of acetaminophen in Fischer 344 rats. The present studies were designed to characterize th