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Additions and Corrections - Intramolecular Type II "Metallo-Ene" Reactions of (2-Alkenylallyl)magnesium Chlorides: Regio- and Stereochemical Studies

โœ Scribed by Oppolzer, Wolfgang; Pitteloud, Rita; Strauss, Henrich


Book ID
127036437
Publisher
American Chemical Society
Year
1983
Tongue
English
Weight
128 KB
Volume
105
Category
Article
ISSN
0002-7863

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Practical preparation and metallo-ene re
โœ Wolfgang Oppolzer; Philippe Schneider ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 212 KB

Magnesium activated by equilibratiog with its anthracene adduct in THF metalates smoothly 2-alkenyl chlorides at -65 C without significant coupling. The resulting solutions of Grignard reagents are subjected to thermal (80-130ยฐC) cyclization followed by trapping with electrophiles.