Additions and Corrections, "Ferric Chloride in Acetic Anhydride. A Mild and Versatile Reagent for the Cleavage of Ethers"
โ Scribed by Ganem, Bruce; Small, Jr., Vernon
- Book ID
- 127351743
- Publisher
- American Chemical Society
- Year
- 1975
- Tongue
- English
- Weight
- 141 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
A novel method for the preparation of 1,6-anhydro glucopyranoses (mono-and disaccharides) utilizing anhydrous FeCl 3 as Lewis acid is described. Treatment of methyl 6-O-benzyl and 6-O-p-methoxybenzyl-a/b D-glucopyranosides derivatives with FeCl 3 in CH 2 Cl 2 at room temperature and 40ยฐC afforded 1,
Lithium Tetrafluoroborate: A Mild and Efficient Reagent for the Cleavage of Dimethoxytrityl Ethers. -LiBF 4 is a mild and highly efficient reagent for the cleavage of Dmt ethers (I). Functional groups such as silyl, isopropylidene, ester and epoxide as well as nucleotide bonds are not effected.
Ababuctz nle selective clesvage ofprimary sml secondsty trimethylsilyl (TMS). abopmpylsilyl (TIPS), tut-butyldimahylsilyl~DMS)rrndtut-butyldiphnylsilyl~DPS)ahaswithwrtral~urminr\mdaverymildconditions is described. The method involvea tdiktkm of the support, pwiously activated by hesting at WC/O. 1 t
A mild and efficient neutral aqueous method for selective cleavage of acetals and ketals to the corresponding carbonyl compounds has been established by using LiCI in H20-DMSO at elevated temperature. While aryl and ~,~-unsaturated ketals and acetals underwent smooth cleavage, diaryl, non-aryl and i