Additions and Corrections, "A Reagent for the αβ Reduction of Conjugated Nitriles."
✍ Scribed by Profitt, James; Watt, David; Corey, E.
- Book ID
- 126136905
- Publisher
- American Chemical Society
- Year
- 1975
- Tongue
- English
- Weight
- 141 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
It has been shown that over-all conversions of carbonyl compounds to olefins, similar to the well known "Wittig" reaction, could be effected using silicon-substituted carbanions 1 . Recently, an alkyl lithiomethylacetate was reported to be an excellent reagent for the synthesis of a,%-unsaturated ca
a-Alkoxystannane J-was prepared by the method by Still.la Transmetallation with nBuLi in THF at -78'C and addition of the lithio anion to a solution of cyclohexenone produced the unstable 1,2-addition product 2. -GC analysis of the crude product mixture indicated that no 1,4-addition had occurred. C