Additions and Corrections - Reactions of Dianions of Carboxylic Acids with Esters and αβ-Unsaturated Esters, Nitriles, and Aldehydes
✍ Scribed by Kuo, Yu-Neng; Yahner, Joseph; Ainsworth, C.
- Book ID
- 125929677
- Publisher
- American Chemical Society
- Year
- 1972
- Tongue
- English
- Weight
- 119 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0002-7863
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## Abstract Treatment of 3‐methylamino‐5‐phenylthiophene with α,β‐unsaturated esters, __i.e.__, methyl acrylate, (__E__)‐methyl crotonate, diethyl fumarate, diethyl maleate and ethyl propiolate, in tetrahydrofuran for several days at reflux gave 1‐methyl‐3,4‐dihydrothieno[2,3‐__e__]pyridin‐2‐ones *
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The reactions of a,b-unsaturated aldehydes such as (E)-cinnamaldehyde and 2-or 4-methoxycinnamaldehyde with trimethylsilyl cyanide in the presence of a catalytic amount of a Lewis base such as TTMPP and DBU afforded the corresponding saturated carboxylic acids after hydrolysis.