Addition of mercaptans to acetylenic γ-hydroxy ketones
✍ Scribed by A. S. Medvedeva; L. P. Safronova; M. G. Voronkov
- Book ID
- 112440411
- Publisher
- Springer
- Year
- 1973
- Tongue
- English
- Weight
- 108 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1573-9171
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📜 SIMILAR VOLUMES
The reaction of l-pmethoxyphenyl-3-phenyl-2-propen-l-one and 3-gmethoxyphenyl-l-phenyl-2-propen-lone with methylhydrazine gave 1-methyl-3-p-methoxyphenyl-S-phenylpyrazoline and l-methyl-3-phenyl-Sp-methoxyphenylpyrazoline, respectively. These compounds, on oxidation, gave 1-methyl-3-p-methoxyphenyl-
g-Hydroxy-a,b-acetylenic esters containing three adjacent and structurally very different functional groups are very useful in the synthesis of highly functionalized organic molecules. [1, 2] This class of compound is normally prepared by treatment of an alkyl propiolate with nBuLi at À78 8C