Conventional ionic bromination of electron-poor olefins. Z-(l-hydroxyalkyl)-and 2-( laikoxyalkyl)propenoates, 2d, and methyl Q-2-(I-hydroxyethyl)-Z-butenoate, 3a, proceeds with yields higher than 80%. Treatmeat of (E)-3-bromo-2-[1-[(2-methoxyethoxy)methoxy]butyl]propenoic acid, 16, with two equivale
Addition of chlorine, bromine and bromine chloride to some α,β-unsaturated methyl esters
✍ Scribed by Ilpo O.O. Korhonen; Maija Pitkänen; Jorma N.J. Korvola
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 441 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract The first example of an organocatalytic asymmetric Michael addition of aldehydes to α,β‐unsaturated thiol esters promoted by chiral diphenylprolinol silyl ether is presented. The reaction occurs with good yields, diastereoselectivity and excellent enantioselectivity.
The effective conjugate addition of a dimethyl phosphonate moiety to a&unsaturated esters and kefones is described. This addition is promoted specifically by trimethylaluminum and does not occur with other Lewis acids which have been examined to date.