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Acyclopyrimidine C-nucleosides: Synthesis of 5-[(2,3-dihydroxy-1-propoxy)methyl]pyrimidines

โœ Scribed by Chung K. Chu; Jungjin Suh

Book ID
112128397
Publisher
Journal of Heterocyclic Chemistry
Year
2009
Tongue
English
Weight
333 KB
Volume
23
Category
Article
ISSN
0022-152X

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Synthesis of 4-Substituted 1-((2,3-Dihydroxy-1-propoxy)methyl)-1Hpyrazolo (3,4-d)pyrimidines. -The regioselective synthesis of a series of acyclonucleosides of pyrazolopyrimidines (cf. (IV), (V), (VII), (IX)) is described. The obtained compounds are evaluated for their cytotoxicity and anti-HIV act