Monosomy 21 and metacentric markers corresponding in size to chromosomes 8 to 12 were found as the only clonal chromosomal changes in a child with acute lymphoblastic leukemia (ALL). Chromosome painting with a whole chromosome 2 I -specific probe showed that the marker originated from chromosome 2 I
β¦ LIBER β¦
Acute lymphoblastic leukemia in a child with constitutional ring chromosome 21
β Scribed by Angela M. Falchi; Maria G. Orofino; Anna L. Nucaro; Stefano De Virgiliis; Antonio Cao
- Book ID
- 119103383
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 606 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0165-4608
No coin nor oath required. For personal study only.
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## Abstract Fluorescence in situ hybridization (FISH) studies were performed in three cases of acute lymphoblastic leukemia (ALL) with marker chromosomes to analyze the contribution of chromosome 21 in these markers. FISH with a chromosome 21 painting probe confirmed that chromosome 21 was involved
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