Suppression of human cartilage proteogly
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B. Wilbrink; M. Holewijn; J. W. J. Bijlsma; J. L. A. M. Van Roy; W. Den Otter; W
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Article
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1993
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John Wiley and Sons
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English
β 454 KB
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Objective. To examine whether T cell reactivity toward heat-shock proteins (HSP) contributes to cartilage destruction in rheumatoid arthritis (RA). Methods. An in vitro system was used, in which human cartilage explants were cocultured with hsp60activated synovial fluid mononuclear cells (SFMC) fro