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Activation of serum response factor in the liver of Long-Evans Cinnamon (LEC) rat

โœ Scribed by Yutaka Maeda; Takahiro Taira; Kensaku Haraguchi; Kyogo Hirose; Akio Kazusaka; Shoichi Fujita

Book ID
117468573
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
882 KB
Volume
119
Category
Article
ISSN
0304-3835

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The Long Evans Cinnamon (LEC) rat develo
The Long Evans Cinnamon (LEC) rat develops hepatocellular damage in the absence of antimicrosomal antibodies
โœ Karen Bedard; I.Carmen Fuentealba; Alastair Cribb ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 743 KB

Long Evans Cinnamon (LEC) rats are an inbred strain with a mutation affecting a copper transporter. As a result, hepatic copper levels rise and the rats spontaneously develop hepatitis that is fatal in about 40% of the rats. The rats that die have been reported to develop anti-microsomal antibodies,