✦ LIBER ✦

Activation of mouse peritoneal macrophages by mannophosphoinositides of mycobacteria

✍ Scribed by P. K. Mehta; Gopal K. Khuller

Publisher: Springer-Verlag
Year: 1989
Tongue: English
Weight: 375 KB
Volume: 178
Category: Article
ISSN: 0300-8584
DOI: 10.1007/bf00202288

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✦ Synopsis

Peritoneal macrophages isolated from mannoside-methylated bovine serum albumin (MBSA)-immunized mice showed significantly enhanced phagocytosis of Mycobacterium smegmatis compared to control or MBSAimmunized groups. Immune macrophages also exhibited bacteriostatic activity against M. smegmatis. Pretreatment of mycobacteria with mannoside antibodies did not further alter the phagocytosis and bacteriostatic effect of immune macrophages.

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