𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Resorption of bone by mouse peritoneal macrophages

✍ Scribed by T. J. Chambers

Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
274 KB
Volume
135
Category
Article
ISSN
0022-3417

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

An experimental system is described in which mononuclear phagocytes are shown to cause contact‐dependent resorption of bone powder in vitro. Endotoxin, which is known to stimulate macrophage functions, and which has also been shown to increase bone resorption in organ culture, increased bone dissolution by mononuclear phagocytes. On the other hand, parathyroid hormone and prostaglandin E~2~, hormones which increase the number and activity of osteoclasts, had no effect on resorption of bone powder by monnuclear phagocytes. This suggests that the osteoclast, which is probably derived from mononuclear phagocytes, is induced to respond to these hormones indirectly, following a primary hormonal effect on osteoblasts.

πŸ“œ SIMILAR VOLUMES

Activation of mouse peritoneal macrophag
Activation of mouse peritoneal macrophages by mannophosphoinositides of mycobacteria
✍ P. K. Mehta; Gopal K. Khuller πŸ“‚ Article πŸ“… 1989 πŸ› Springer-Verlag 🌐 English βš– 375 KB

Peritoneal macrophages isolated from mannoside-methylated bovine serum albumin (MBSA)-immunized mice showed significantly enhanced phagocytosis of Mycobacterium smegmatis compared to control or MBSAimmunized groups. Immune macrophages also exhibited bacteriostatic activity against M. smegmatis. Pret

Heterogeneity of concanavalin A binding
Heterogeneity of concanavalin A binding by mouse peritoneal macrophages
✍ R. Water; C. A. Blitterswijk; W. Th. Deams; L. A. Ginsel πŸ“‚ Article πŸ“… 1982 πŸ› Springer 🌐 English βš– 900 KB

The binding of the lectin concanavalin A (Con A) to the cell surface of monocytes and macrophages collected from the stimulated peritoneal cavity of mice was investigated electron microscopically with horseradish peroxidase-gold as an indirect marker. Individual cells were identified by the cytochem