Activity of 06-methylguanine-DNA methyltransferase (MGMT) is well related with drug resistance of tumor cells to chloroethylnitrosoureas (CENUs), because MGMT removes CENU-induced O6-alkyIguanines in DNA by accepting the alkyl group at a cysteine moiety. Inactivation of MGMT is a feasible way to ove
Activation of human O6-methylguanine-DNA methyltransferase gene by glucocorticoid hormone
β Scribed by Biswas, Tapan; Ramana, Chilakamarti V; Srinivasan, Ganesan; Boldogh, Istvan; Hazra, Tapas K; Chen, Zhenping; Tano, Keizo; Thompson, E Brad; Mitra, Sankar
- Book ID
- 110061777
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 420 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0950-9232
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