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Activation of HER2 pathway induces expression of cyclooxygenase-2, release of prostaglandin E2, and mitogenesis in human colorectal cancer cells

✍ Scribed by Kumar, Rakesh; Mandal, Mahitosh; Adam, Liana; Bandyopadhyay, Debdutta; Steinbach, Gideon; Mendelsohn, John; Valdamudi, Ratna

Book ID
122033168
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
237 KB
Volume
114
Category
Article
ISSN
0016-5085

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## Abstract Thrombin levels increase at sites of vascular injury and during acute coronary syndromes. It is also increased several fold by sepsis with a reciprocal decrease in the anti‐thrombin III levels. In this study we investigate the effects of thrombin on the induction of cyclooxygenase‐2 (CO