The peripheral blood from 15 patients with primary Sjögren's syndrome and from 15 matched controls was examined for the presence of activated T and B lymphocytes, by using monoclonal antibodies directed to interleukin-2 (IL-2) and transferrin receptors, and to HLA-DR determinants. The number of circ
✦ LIBER ✦
Activation-induced cell death of peripheral blood T lymphocytes in patients with primary Sjögren’s syndrome
✍ Scribed by Ogawa, Noriyoshi ;Karahashi, Taro ;Akamine, Noriko ;Goto, Yoshinori ;Ohashi, Hiroyuki ;Ohno, Ryuzo
- Publisher
- Informa UK (Informa Healthcare)
- Year
- 1999
- Tongue
- English
- Weight
- 769 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0169-1163
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## Abstract ## Objective To delineate disturbances in peripheral B cell memory in primary Sjögren's syndrome (SS). ## Methods Isotype‐specific immunoglobulin (Ig) heavy‐chain transcripts were analyzed in single‐sorted CD19+,CD27− naive and CD19+,CD27+ memory B cells from patients with primary SS
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