The peripheral blood from 15 patients with primary Sjögren's syndrome and from 15 matched controls was examined for the presence of activated T and B lymphocytes, by using monoclonal antibodies directed to interleukin-2 (IL-2) and transferrin receptors, and to HLA-DR determinants. The number of circ
✦ LIBER ✦
Abnormal immunoglobulin and rheumatoid factor synthesis by blood lymphocytes in patients with primary Sjögren's syndrome
✍ Scribed by Martjn A. Rodriguez; Miren L. Baroja; Matilde Leon-Ponte; Isaac Abadi
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 952 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective To delineate disturbances in peripheral B cell memory in primary Sjögren's syndrome (SS). ## Methods Isotype‐specific immunoglobulin (Ig) heavy‐chain transcripts were analyzed in single‐sorted CD19+,CD27− naive and CD19+,CD27+ memory B cells from patients with primary SS
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