Activated nitriles in heterocyclic synthesis: Novel syntheses of 3H-1,2,4-triazolo-[1,5-a]pyridine derivatives
β Scribed by Suzan I. Aziz; Zaghloul E. Kandeel; Mona M. Husein; Salem El Gohary; Eiman I. Abou El Maged
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 311 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1042-7163
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β¦ Synopsis
Abstract
A new route for the synthesis of 3Hβ1,2,4βtriazolo[1,5βa]pyridines 7aβj, 12a,b, and 17a,b utilizing the reaction of the hydrazones of cyanoethanoic acid hydrazide 3a,b with ylidene malononitriles 2aβe, malononitrile, and 3βaminocrotononitrile is described.
π SIMILAR VOLUMES
## Abstract A series of novel antifungal triazole derivatives 2βarylβ1,2,4βtriazolo[1,5βa]pyridine **9aβm** were synthesized and tested __in vitro__ for their growth inhibitory activities against __C. albicans__ and __T. rubrum__. The MIC values indicate that the activities of three compounds were
Synthese von 2H-1,2,3-Triazolo[4,5-~][1,2,4]triazolo[4,3-a]pyridinen und verwandten Systemen Zur Herstellung des 2H-1,2,3-Triazolo[4,5-c]pyridin-4(5H)-ons 4 wurde 2-Phenyl-2H-l,2,3triazol-4-carbaldehyd (1) zunichst in die Acrylsiiure 2 umgewandelt und letztere dann nach vorausgehender Curtius-Umlage