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Synthesis and Antifungal Activity of 2-Aryl-1,2,4-triazolo[1,5-a]pyridine Derivatives

✍ Scribed by Yun Luo; Yongzhou Hu

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
895 KB
Volume
339
Category
Article
ISSN
0365-6233

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✦ Synopsis

Abstract

A series of novel antifungal triazole derivatives 2‐aryl‐1,2,4‐triazolo[1,5‐a]pyridine 9a–m were synthesized and tested in vitro for their growth inhibitory activities against C. albicans and T. rubrum. The MIC values indicate that the activities of three compounds were superior or comparable to fluconazole against both tested fungi, worthy of further investigation of its antifungal activities.

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