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Activated Alzheimer Disease Platelets Retain More Beta Amyloid Precursor Protein

✍ Scribed by T.A Davies; H.J Long; K Sgro; W.H Rathbun; M.E McMenamin; K Seetoo; H Tibbles; A.M Billingslea; R.E Fine; J.B Fishman; C.A Levesque; S.J Smith; J.M Wells; E.R Simons

Book ID: 117414195
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 499 KB
Volume: 18
Category: Article
ISSN: 0197-4580
DOI: 10.1016/s0197-4580(97)00013-4

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## Abstract Proteolytic processing of the amyloid precursor protein by β ‐and γ‐secretases results in the production of Alzheimer's disease (AD) Aβ amyloid peptides. Modulation of secretase activity is being investigated as a potential therapeutic approach. Recent studies with human brain have reve