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Platelet amyloid precursor protein processing: A bio-marker for Alzheimer's disease

✍ Scribed by Kun Tang; Linda S. Hynan; Fred Baskin; Roger N. Rosenberg

Book ID
119301819
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
337 KB
Volume
240
Category
Article
ISSN
0022-510X

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## Abstract Proteolytic processing of the amyloid precursor protein by Ξ² ‐and γ‐secretases results in the production of Alzheimer's disease (AD) AΞ² amyloid peptides. Modulation of secretase activity is being investigated as a potential therapeutic approach. Recent studies with human brain have reve