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Actions of epoxyeicosatrienoic acid on large-conductance Ca2+-activated K+ channels in pituitary GH3 cells

โœ Scribed by Sheng-Nan Wu; Hui-Fang Li; Hung-Ting Chiang


Book ID
113992301
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
696 KB
Volume
60
Category
Article
ISSN
0006-2952

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Polyamines block Ca2+-activated K+channe
โœ T. Weiger; A. Hermann ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Springer ๐ŸŒ English โš– 800 KB

The effects of the natural polyamines, putrescine, spermidine and spermine on single calcium-activated potassium channels from clonal rat pituitary tumor cells (GH3) were studied. Applied to inside-out patches, polyamines were found to reduce the current amplitude and open probability of the channel