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Actions of 4-(2-hydroxy-3-[(1-methyl-3-phenylpropyl)amino]propoxy)benzeneacetamide (KF4317) and labetalol on α- and β-adrenoceptors

✍ Scribed by Takayanagi, Issei; Koike, Katsuo; Konno, Fukio; Hiruta, Tsuyoshi; Kusunoki, Masataka; Sato, Takahiro; Toyoda, Jiro; Kizawa, Yasuo

Book ID
122979087
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
222 KB
Volume
17
Category
Article
ISSN
0306-3623

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## Abstract Aldol reaction of 7‐chloro‐1,3‐dihydro‐1‐methyl‐5‐phenyl‐2__H__‐1,4‐benzodiazepin‐2‐one (**1**) with 4‐substituted __α__‐methylcinnamaldehydes **2**–**5** afforded a mixture of __threo__‐ and __erythro__‐3‐(3‐aryl‐1‐hydroxy‐2‐methylprop‐2‐enyl)‐7‐chloro‐1,3‐dihydro‐1‐methyl‐5‐phenyl‐2__