Calcium cyclamate, an artificial sweetener, was studied for its effectiveness in inducing transmissible chromosomal aberrations in germ cells of male mice. Both the dominant-lethal and the heritable translocation tests were carried out following daily treatment (on weekdays) of males by oral intubat
Acrylamide: Induction of heritable translocations in male mice
β Scribed by Shelby, M. D. ;Cain, K. T. ;Cornett, C. V. ;Generoso, W. M.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1987
- Weight
- 410 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0192-2521
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The objectives of this research were: 1) to investi-PAINT/DAPI analysis revealed that: 1) AA-induced gate the time course of the cytogenetic defects in-chromosomal breaks occurred at random, and 2) duced by acrylamide (AA) treatment (5 1 50 mg/ the frequencies of symmetrical and asymmetrical kg) of
## Abstract The formation of acrylamide during heating of certain foodstuffs constitutes a potential health hazard. The health risk assessment should be based on knowledge about the relation between dietary exposure to acrylamide and internal doses of acrylamide and its genotoxic metabolite glycida