Kinetics of alkaline isomerization and h
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T. O. Oesterling; C. M. Metzler
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Article
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1972
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John Wiley and Sons
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English
β 413 KB
In alkaline media the 2-, 3-, and Cmonohexanoates of lincomycin rapidly isomerize, each entering into facile equilibrium with the other two, accompanied by hydrolysis of each species to lincomycin. The concentration-time curves of the three esters and of lincomycin as observed in a single experiment