Accuracy Profile Theory for the Validation of an LC–MS-MS Method for the Determination of Risperidone and 9-Hydroxyrisperidone in Human Plasma
✍ Scribed by Xianhua Zhang; Xia Zhao; Chao Zhang; Li Yang; Xin Xiong; Yong Zhou; Yiheng Yang; Jingli Duan
- Book ID
- 111792002
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 613 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0009-5893
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A sensitive LC-MS-MS method capable of quantifying terfenadine at levels down to 100 pg ml-1 in human plasma is reported. The method was validated over a linear range from 0.1 to 5.0 ng ml-1 using a liquid-liquid extraction with a deuterium-labelled internal standard. The between-run precision and a
A sensitive and specific LC/MS/MS method for the determination of L-hyoscyamine was developed and validated over the linearity range 20-500 pg ml-1 with 1.0 ml of plasma using scopolamine as the internal standard. The API III-Plus LC/MS/MS was operated under the multiple reaction monitoring mode usi