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Accounting for Bias in Estimates of the Rate of Polygenic Mutation

โœ Scribed by Peter D. Keightley, Trudy F. C. Mackay and Armando Caballero


Book ID
123642522
Publisher
The Royal Society
Year
1993
Tongue
English
Weight
902 KB
Volume
253
Category
Article
ISSN
0080-4649

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An algorithm is described for calculating the probability distribution of the number of mutant colonies arising in a Luria-Delbrtick fluctuation experiment subject to a plating efficiency of less than 100%. A table is constructed to facilitate the estimation of spontaneous mutation rates taking into