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Accounting for Bias in Estimates of the Rate of Polygenic Mutation

โœ Scribed by Keightley, P. D.; Mackay, T. F. C.; Caballero, A.


Book ID
120141379
Publisher
The Royal Society
Year
1993
Tongue
English
Weight
980 KB
Volume
253
Category
Article
ISSN
0080-4649

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An algorithm is described for calculating the probability distribution of the number of mutant colonies arising in a Luria-Delbrtick fluctuation experiment subject to a plating efficiency of less than 100%. A table is constructed to facilitate the estimation of spontaneous mutation rates taking into