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Accommodating fluorinated amino acids in a helical peptide environment

โœ Scribed by Nyakatura, Elisabeth K.; Reimann, Oliver; Vagt, Toni; Salwiczek, Mario; Koksch, Beate


Book ID
121276407
Publisher
The Royal Society of Chemistry
Year
2013
Tongue
English
Weight
741 KB
Volume
3
Category
Article
ISSN
2046-2069

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Incorporation of easily available achiral w-amino acid residues into an oligopeptide results in substitution of amide bonds by polymethylene units of an aliphatic chain, thereby providing a convenient strategy for constructing a peptidomimetic. The central Gly-Gly segment of the helical octapeptide