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A measure of helical propensity for amino acids in membrane environments

โœ Scribed by Li, Shun-Cheng ;Deber, Charles M.


Book ID
109964871
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
544 KB
Volume
1
Category
Article
ISSN
1545-9993

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The relative order of helical propensity
โœ Chartchai Krittanai; W. Curtis Johnson Jr ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 158 KB

A model peptide of sequence Ac-Y-VAXAK-VAXAK-VAXAK-NH 2 , where X is substituted with one of nineteen amino acids (P excluded), was synthesized and titrated with methanol to study helical propensity as a function of solvent environment. The CD spectra of these peptides are largely random coil in 2 m