Acceptance of and Attitude Toward Genetic Testing for Hereditary Nonpolyposis Colorectal Cancer: A Comparison of Participants and Nonparticipants in Genetic Counseling
✍ Scribed by Monika Keller; Ralf Jost; Martina Kadmon; Hans-Peter Wüllenweber; Carrie Mastromarino Haunstetter; Frank Willeke; Christine Jung; Johannes Gebert; Christian Sutter; Christian Herfarth; Markus W. Büchler
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 209 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0012-3706
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
We thank Ms. Jeanne Wenger and Ms. Linda M. Welch for secretarial assistance.
Hereditary nonpolyposis colorectal carcinoma (HNPCC) is the most common hereditary form of colorectal carcinoma (CRC) and may account for 5-10% of the total CRC burden. The discovery of DNA mismatch repair (MMR) genes, inclusive of hMSH2, hMLH1, hPMS2, and hMSH6, has enabled the identification of wh
## Background: Molecular testing for hereditary nonpolyposis colorectal carcinoma (hnpcc) is becoming standard care and it is cost-effective compared with no genetic testing. however, the best strategy for detection of hnpcc gene carriers is unknown. ## Methods: We use a decision analytic model t